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References – Folate, NOT Folic Acid is What You Need

  1. Neil Rawlins, MD – Kadlec Regional Medical Center. N.p., 2016. Web. 5 Mar. 2016.
  2. Greenberg JA, Bell SJ, Guan Y, Yu YH. Folic Acid supplementation and pregnancy: more than just neural tube defect prevention. Rev Obstet Gynecol. 2011;4(2):52-9.
  3. MTHFR Gene Mutation | Disease | Tests & Diagnosis | Genetic And Rare Diseases Information Center (GARD) – An NCATS Program. N.p., 2016. Web. 3 Mar. 2016.
  4. Scaglione F, Panzavolta G. Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica. 2014;44(5):480-8.
  5. Hsu HC, Chiou JF, Wang YH, et al. Folate deficiency triggers an oxidative-nitrosative stress-mediated apoptotic cell death and impedes insulin biosynthesis in RINm5F pancreatic islet β-cells: relevant to the pathogenesis of diabetes. PLoS ONE. 2013;8(11):e77931.
  6. Wu LL, Wu JT. Hyperhomocysteinemia is a risk factor for cancer and a new potential tumor marker. Clin Chim Acta. 2002;322(1-2):21-8.
  7. Guthikonda S, Haynes WG. Homocysteine: role and implications in atherosclerosis. Curr Atheroscler Rep. 2006;8(2):100-6.
  8. Ambrosino P, Lupoli R, Di minno A, et al. Cyclic supplementation of 5-MTHF is effective for the correction of hyperhomocysteinemia. Nutr Res. 2015;35(6):489-95.
  9. Mcgarel C, Pentieva K, Strain JJ, Mcnulty H. Emerging roles for folate and related B-vitamins in brain health across the lifecycle. Proc Nutr Soc. 2015;74(1):46-55.
  10. Available at: Accessed February 15, 2016.
  11. Delchier N, Ringling C, Le grandois J, et al. Effects of industrial processing on folate content in green vegetables. Food Chem. 2013;139(1-4):815-24.
  12. Schwammenthal Y, Tanne D. Homocysteine, B-vitamin supplementation, and stroke prevention: from observational to interventional trials. Lancet Neurol. 2004;3(8):493-5.
  13. Willems FF, Boers GH, Blom HJ, Aengevaeren WR, Verheugt FW. Pharmacokinetic study on the utilisation of 5-methyltetrahydrofolate and folic acid in patients with coronary artery disease. Br J Pharmacol. 2004;141(5):825-30.